Herpes simplex virus (HSV) is … episode infection is the first genital HSV infection in an individual who has Screening for Genital Herpes Simplex: … The safety of valacyclovir and … Screening for Genital Herpes Simplex: Brief Update for the U.S. Preventive Services Task Force Screening for Genital Herpes Simplex: A Brief Update Herpes simplex virus (HSV) is a DNA viruswith 2 subtypes: herpes simplex virus 1(HSV-1) and herpes simplex virus 2 (HSV-2). Although each is a distinct virus, they share some antigenic components.

Herpes simplex virus (HSV) is a DNA viruswith 2 subtypes: herpes simplex virus 1 (HSV-1) and herpes simplex virus 2 (HSV-2). Although each is a distinct virus, they share some antigenic components. HSV causes vesicular and ulcerative lesions in healthy individuals and may cause severe systemic disease in neonates and immunosuppressed hosts.1Infection with HSV-1 commonly causes oropharyngeal infection, and transmission is primarily by non-genital personal contact, whereas infection with HSV-2 most often results in genital lesions, and transmission isusually sexual.1,2However, either virus may causeoropharyngeal or genital infection and can produce mucosal lesions that are clinically indistinguishable.1,3 HSV is the most prevalent sexually transmitted disease (STD) in the United States.3The most accurate estimates derived from seroprevalence surveys show that 1 person in 5, aged 12 years and older in the United States, has been infected with HSV-2, and the rate is even higher among adults and women.1These estimates do not include the contribution of sexually acquired HSV-1 to the epidemic of genital herpes. An estimated 1.6million new HSV-2 infections occur in the United States annually. 4…

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